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CYCLO(-HIS-PHE) CAS 56586-95-9
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CYCLO(-HIS-PHE) CAS 56586-95-9

CAS : 56586-95-9
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CYCLO(-HIS-PHE) CAS 56586-95-9 Product Information

CAS No

56586-95-9

Product  Name

CYCLO(-HIS-PHE)

Synonyms

CYCLO(-HIS-PHE);

cyclo(histidine-phenylalanine);

2,5-Piperazinedione, 3-(1H-imidazol-5-ylmethyl)-6-(phenylmethyl)-, (3S,6S)-;

cyclo(Phe-His);

Cyclo(histidylphenylalanine)

Free SampleAvailable
Molecular FormulaC15H16N4O2
Molecular Weight284.31
Purity99%
Free ShippingYES



CYCLO(-HIS-PHE) CAS 56586-95-9 Chemical Properties

Melting point259-263 °C (decomp)
Boiling point722.4±50.0 °C(Predicted)
Density1.294±0.06 g/cm3(Predicted)
Storage conditions-20°C
Acidity coefficient (pKa)12.71±0.60(Predicted)
Color
 white
Formpowdered solid
SourceArtificial chemical synthesis is limited to scientific research use and may not be used on the human body.
Salt systemOptional TFA, HAc, HCl or others
Generation cycle2-3 weeks









CYCLO(-HIS-PHE) CAS 56586-95-9 Uses And Synthesis Methods

  • Biological activity

Cyclo(-His-Phe) is a catalyst for asymmetric cyanohydrin synthesis. The addition of hydrogen cyanide to benzaldehyde gives the highest optical yield ever obtained for the corresponding cyanohydrin. In a study of McCleland et al., Cyclo(His-Phe) showed significant anti-tumour activity, causing reduction of cell viability in cervical cancer cells. In isolated rat hearts, the diketopiperazine caused a gradual reduction of heart rate and a decrease in coronary flow rate.


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CYCLO(-HIS-PHE) CAS 56586-95-9 56586-95-9 Cyclo(histidylphenylalanine) cyclo(histidine-phenylalanine)

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