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CAS 529-35-1 5,6,7,8-TETRAHYDRO-1-NAPHTHOL
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CAS 529-35-1 5,6,7,8-TETRAHYDRO-1-NAPHTHOL

CAS ：529-35-1
MOQ：1KG
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CAS 529-35-1  5,6,7,8-TETRAHYDRO-1-NAPHTHOL Product Information

Product name 

5,6,7,8-TETRAHYDRO-1-NAPHTHOL

CAS number

529-35-1 

Molecular formula

C10H12O

Molecular weight

148.2

Purity

99%


CAS 529-35-1  5,6,7,8-TETRAHYDRO-1-NAPHTHOL Properties

Melting point69-71 °C(lit.)

Boiling point

264-265 °C705 mm Hg(lit.)

Density

1.0556

Refractive index

1.5000 (estimate)

Acidity coefficient (pKa)

pK1:10.28 (25°C)
Flash point264-265°C/705mm

Storage conditions

Inert atmosphere,Room Temperature
Condition to AvoidAir Sensitive

Form

solid
Coloroff-white to light orange
SolubilitySoluble in chloroform (a little), methanol (a little)
BRN1865081
InChIKeySCWNNOCLLOHZIG-UHFFFAOYSA-N


GHS

Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.


CAS 529-35-1 5,6,7,8-TETRAHYDRO-1-NAPHTHOL Chemical Properties,Uses,Production

  • Category

    Chemical reagents: polycyclic compounds

  • Uses

       5,6,7,8-Tetrahydro-1-naphthol is a useful chemical intermediate, widely applied in organic synthesis and also used as a fuel additive.

  • Industrial Production

       5,6,7,8-Tetrahydro-1-naphthol can be produced through partial reduction of aromatic ring of 1-naphthol by various homogeneous or heterogeneous catalytic hydrogenation methods.

  • Chemical Properties

      white to slightly pink crystalline mass or

  • Uses

      5,6,7,8-Tetrahydro-1-naphthalenol was used as a reagent in the synthesis of phosphonamidate and phosphonodiamidate prodrugs of adefovir and tenofovir which are used in the treatment of HIV infections. Also used in the synthesis of tetrahydronaphthalene-1-ol derivatives which were found to be promising potent antitumor agents.

  • Definition

    ChEBI: 5,6,7,8-tetrahydro-1-naphthol is 1-naphthol hydrogenated at C-5, -6, -7 and -8.


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